Advances in genetic and genomic techniques have provided potential tools for the study of many rare diseases. Our company is committed to the continuous improvement of the accuracy and affordability of high-throughput technologies to help customers identify gene variants related to rare diseases, accelerate customers' research on the molecular mechanism of rare diseases, allow better...

The availability of animal models that mimic human diseases has greatly increased our understanding of neuromuscular rare disease pathology. Our company is committed to providing our clients with a wide range of animal models, including not only naturally occurring animal models but also custom models carrying specific mutations. Our advances in gene editing allow us to help our clients develop...

Cell-based model is a crucial tool widely used in the early stage of drug development, which is a generalized modular approach to simulate the disease pathogenesis and detect drug response in vitro in biomedical research of rare diseases. Cell-based Models for Rare Disease Cell-based models, with far-ranging applications in most drug screening and drug-target interaction...

Understanding animal behavior: These tests help researchers gain insight into how animals think, learn, and solve problems. By conducting cognitive behavioral tests, scientists can better understand the cognitive abilities of different animal species and how they compare to humans.   Comparative studies: Comparative cognition research is important for understanding the evolution of...

Silica-based vectors are attractive as gene transfer vehicles due to their high stability, safety, and ease of structural and surface modification. A variety of silica-based vectors for gene delivery have been reported, including silica nanotubes (SNT), silica sheets, and silica NPs (solid (non-porous) silica NPs and porous silica NPs). Among these, silica NPs have been extensively investigated...

Studies have shown that SLNs can concentrate DNA onto nanometer colloidal particles and can effectively transfect mammalian cells in vitro. SLN offers several technical advantages over standard DNA or RNA carriers such as cationic lipids or cationic polymers, including large-scale production from substances generally recognized as safe, high storage stability, and suitability for steam...

In the field of scientific research, understanding and studying emotion-related behaviors in animals plays a crucial role in advancing the knowledge of the human brain and mental health. Animal models can help researchers better comprehend animal behaviors, and rodent models in particular have become important objects for understanding the mechanisms of emotional behaviors and...

What is cystic fibrosis? Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates chloride ions transport across cell membranes. These mutations cause the CFTR protein to be either absent or not function...